Substitutionsarbete och utveckling av PRIO-guiden
L416 Lysate, Nuclease Treat - Promega Corporation
The REACH Regulation pays specific attention to the PBT/vPvB concern. One aim of the REACH Regulation is the substitution of PBT and vPvB substances where suitable technically and economically viable alternatives are available. Until the substitution is achieved, the releases of and exposures to PBT CMR (Carcinogénico, Mutagénico em células germinativas ou tóxico para a Reprodução), Cat. 1A, 1B (Regulamento CLP); PBT (Persistente, Bioacumulável e Tóxico), mPmB (muito Persistente e muito Bioacumulável); cmr / pbt KREATiS is a unique organisation offering you in silico ecotoxicology, mammalian toxicology and physical chemistry predictions to screen the hazards of your substance or to complete your regulatory dossiers or boost your R&D in the most time and cost efficient way possible using: Se hela listan på kemi.se PBT or vPvB properties”; Consequences for the registrant of the conclusions deriving from the first Step of the PBT/vPvB assessment process are described in the new Section R.11.3.2. Section R.11.3.2.2 is new and describes the situation of substances concluded as being PBT/vPvB by ECHA’s Member State Se hela listan på ri.se POPs (Persistent Organic Pollutants) and Very Persitent and Very Bioaccumulative substances (vPvBs) and Persistent, Bioaccumulative and Toxic substances (PBTs) are generally considered to be substances of very high concern. Substances of very high concern include substances with CMR (Carcinogenic, Mutagenic, reproductive toxic), PBT/vPvB and ED Priority shall be given to registrations of substances which have or may have PBT, vPvB, sensitising and/or carcinogenic, mutagenic or toxic for reproduction (CMR) properties, or substances classified as dangerous according to Directive 67/548/EEC above 100 tonnes per year with uses resulting in widespread and diffuse exposure. SUMMARY FACT SHEET PBT WORKING GROUP – PBT LIST NO. 56 TC NES SUBGROUP ON IDENTIFICATION OF PBT AND VPVP SUBSTANCES RESULTS OF THE EVALUATION OF THE PBT/VPVB PROPERTIES OF: Substance name: Endosulfan EC number: 204-079-4 CAS number: 115-29-7 Molecular formula: C9H6Cl6O3S Structural formula: Status: Fulfils POP screening criteria ECB – SUMMARY FACT SHEET PBT WORKING GROUP – PBT LIST NO. 21 08.11.2007 3 1.2 Physico-Chemical properties Table 1 Summary of physico-chemical properties. For references, see European Commission (2000) REACH ref Annex, § Property Value Comments V, 5.1 Physical state at 20 C and 101.3 Kpa solid Officially classified CMR (carcinogenic, mutagenic and reprotoxic) substances, by default fulfilling REACH SVHC criteria, and for which a non-intermediate use could be expected.
Jun 4, 2019 Are carcinogenic, mutagenic or toxic for reproduction (together known as CMR substances); Are persistent, bioaccumulative and toxic (PBT Dec 1, 2008 Dangerous substances (i.e. CMR, PBT and vPvB > 1% weight ) should be listed in MSDS, only. However, all Material Safety Data Sheets must be Jul 4, 2012 Table 2 Previous SVHC intentions addressing CMR impurities/minor coal- derived substances in Part 3. (d) PBT. (e) vPvB. 13/01/2010.
SÄKERHETSDATABLAD - Merck Millipore
Diphenoxarsin-10-yl oxide. 58- 36-6.
Tilläggsbestämmelser Staffanstorp - Staffanstorps kommun
Because of these factors PBTs have been observed to have a high order of bioaccumulation and biomagnification, very long retention times in will allow use only at the lowest effective level. In addition to the CMR and PBT prohibitions in 5.2, preservatives that release CMRs or PBTs or whose reaction byproducts are CMRs or PBTs will not be allowed. 5.8.3 Special requirements. For colorants, polymers, and preservatives, the toxicological endpoints in the Master These are called CMR substances (Carcinogenic, Mutagenic or Toxic to reproduction.) The second category are harmful substances that do not easily break down and accumulate in the food chain. These are known as PBT substances (short for Persistent, Bio-accumulative and Toxic).
1B (H350). 3 För potentiellt PBT finns kriterier enligt PRIO (se www.kemi.se), som kan användas som underlag vid en
Resultat av PBT- och vPvB-bedömningen. · PBT: Ej användbar. CMR-effekter (cancerframkallande, mutagena och reproduktionstoxiska
2.5 PBT/vPvB Assessment criteria . regarded as a PBT/vPvB substance.
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Management of PBT/vPvB substances under REACH. The REACH Regulation pays specific attention to the PBT/vPvB concern. One aim of the REACH Regulation is the substitution of PBT and vPvB substances where suitable technically and economically viable alternatives are available.
CMR, PBT and vPvB > 1% weight ) should be listed in MSDS, only. However, all Material Safety Data Sheets must be
Jul 4, 2012 Table 2 Previous SVHC intentions addressing CMR impurities/minor coal- derived substances in Part 3.
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Diarienummer: 13LS83 T3.2 Kravspecifikation A B C D E 1 2
Pendimethalin. PBT. Carcinogenic, mutagenic or toxic to reproduction (CMR): Substances meeting anthracene low as a substance of very high concern because of its CMR, PBT contenido de antraceno como sustancia extremadamente preocupante debido a sus propiedades CMR, PBT y MPMB, adoptado el 4 de diciembre de 2009. European Chemicals Agency as persistent, bioaccumulative and toxic ('PBT'; because of its CMR, PBT and vPvB properties, adopted on 4 December 2009. CMR-ämne; PBT; vPvB; ämnen med effekter som motsvarar ovanstående punkter och därför ger anledning till motsvarande oro, till exempel CMR, hormonstörande ämnen, PBT eller vPvB.
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substance of very high concern - Swedish translation – Linguee
•. Potentiella PBT- och vPvB-ämnen (persistenta, bioackumulerande eller CMR - Cancerframkallande 1A,. 1B (H350).